| 9/7/24 |
 Saint Xavier University |
L 7-31 |
Blue Devils Stadium – Southfield, MI |
| 9/14/24 |
 University of St. Francis (Ill) |
L 7-46 |
Joliet Memorial Stadium – Joliet, IL |
| 9/21/24 |
 Marian University |
L 23-24 |
Blue Devils Stadium – Southfield, MI |
| 9/28/24 |
 Judson University |
W 77-18 |
Blue Devils Stadium – Southfield, MI |
| 10/12/24 |
 University of Saint Francis (IN) |
L 14-77 |
Kevin Donley Field at Bishop John M. D’Arcy Stadium |
| 10/19/24 |
 Siena Heights University |
L 14-34 |
Blue Devils Stadium – Southfield, MI |
| 10/26/24 |
 Taylor University |
L 30-48 |
Turner Stadium – Upland, IN |
| 11/2/24 |
 Madonna University |
W 45-28 |
Blue Devils Stadium – Southfield, MI |
| 11/9/24 |
 Concordia Ann Arbor |
L 10-31 |
Cardinal Stadium – Ann Arbor, MI |
| 11/16/24 |
 Indiana Wesleyan |
L 10-58 |
Wildcat Stadium – Marion, IN |
