| 8/31/24 |
 Indiana Wesleyan |
L 0-59 |
Cardinal Stadium – Livonia, MI |
| 9/7/24 |
 Judson University |
L 27-28 |
Millennium Field – Streamwood, IL |
| 9/14/24 |
 Adrian |
L 20-38 |
Docking Stadium – Adrian, MI |
| 9/21/24 |
 Saint Xavier University |
L 13-55 |
Cardinal Stadium – Livonia, MI |
| 9/28/24 |
 University of Saint Francis (IN) |
L 7-70 |
Kevin Donley Field at Bishop John M. D’Arcy Stadium |
| 10/5/24 |
 Olivet Nazarene |
L 15-42 |
Ward Field – Bourbonnais, IL |
| 10/19/24 |
 Concordia Ann Arbor |
L 6-67 |
Cardinal Stadium – Ann Arbor, MI |
| 10/26/24 |
 Defiance College |
L 27-55 |
Justin F. Coressel Stadium – Defiance, OH |
| 11/2/24 |
 Lawrence Tech |
L 28-45 |
Blue Devils Stadium – Southfield, MI |
| 11/9/24 |
 Taylor University |
L 28-91 |
Cardinal Stadium – Livonia, MI |
| 11/16/24 |
 Siena Heights University |
L 3-45 |
Cardinal Stadium – Livonia, MI |
